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Ambrisentan treatment of pulmonary hypertension hypertension Pharmaceutical Grade Ambrisentan CAS:177036-94-1

Categories Pharmaceutical Raw Materials
Brand Name: Hongkong SaiChuang
Model Number: 616204-22-9
Certification: ISO9001
Place of Origin: China
MOQ: 10g
Price: negotiable USD
Payment Terms: Western Union, L/C, , D/A, MoneyGram, T/T, D/P
Supply Ability: 1000KG/month
Delivery Time: within 12 hours after payment
Packaging Details: safe discreet package
Origin: ZheJiang
Name: Ambrisentan
WhatsApp: +86 18873303856
Email: majorina.cai@chembj.com
CAS: 177036-94-1
Tel: +86 18873303856
MF: C22H22N2O4
MW: 378.42
Purity: 99%
Appearance: White crystalline powder
Packaging: discreet packaging
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    Ambrisentan treatment of pulmonary hypertension hypertension Pharmaceutical Grade Ambrisentan CAS:177036-94-1

    Ambrisentan treatment of pulmonary hypertension hypertension Pharmaceutical Grade Ambrisentan CAS:177036-94-1


    Basic INFORMATION


    Name:Ambrisentan

    Molecular Formula: C22H22N2O4

    Molecular Weight: 378.42

    CAS No.: 177036-94-1

    Assay: 99%

    Application : Ambrisentan is a nonpeptide endothelin ETA receptor antagonist and antihypertensive.

    Appearance:Almost white to white crystalline powder

    Storage: Stored in cool & dry place; Kept away from strong light and heat


    What is Ambrisentan​ ​?


    Ambrisentan is a drug used to treat pulmonary hypertension. Peptide endothelin contracts muscles in blood vessels and increases blood pressure. Amphetamine, which relaxes these muscles, is an endothelin receptor antagonist and is selective for type A endothelin receptors. In two double-blind, multicenter trials, Ambrisentan significantly improved exercise capacity compared with placebo.

    Used for?
    Ambrisentan is used to treat high blood pressure in the lungs (pulmonary arterial hypertension). This condition is thought to be caused by increased levels of a certain natural substance (endothelin-1). This medication blocks the effects of endothelin-1, thereby helping to decrease the blood pressure in the lungs, slow the worsening of symptoms, and improve your ability to exercise.
    COA
    ItemSpecificationsResults
    CharacterWhite or white crystalline powderWhite powder
    IdentifyHPLC/UVConforms
    Isomeride≤0.5%0.023%
    Related substanceSingle impurity shall not be over 0.1% Single impurity shall not be over 0.1%Single impurity 0.02%0.031% of the total noise
    Water≤0.5%0.01%
    Residue on ignition≤0.1%0.03%
    Heavy metalMay not have twenty over one million<10ppm
    Assaying98.0%~102.0%99.18%
    ConclusionThe results conforms with enterprise standards

    Function

    Ambrisentan is a drug indicated for use in the treatment of pulmonary hypertension. It functions as an endothelin receptor antagonist, and is selective for the type A endothelin receptor (ETA).


    Application of Ambrisentan :


    Clinical use

    The ambriententa is classified as a WHO class for the treatment of pulmonary arterial hypertension (WHO Group 1) for improvement of morbidity and delayed clinical signs of II or III symptoms.

    Safety and side effects

    Stuffy nose, runny nose, or flushing may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

    Tell your doctor right away if you have any serious side effects, including: fast heartbeat, extreme tiredness, swelling ankles/feet, sudden/unexplained weight gain.

    Other medications that are like ambrisentan may rarely cause very serious liver problems. Tell your doctor right away if you develop symptoms of liver disease, including: persistent nausea/vomiting, loss of appetite, severe stomach/abdominal pain, dark urine, yellowing eyes/skin.

    This medication can decrease sperm production in some men, an effect that may lower male fertility. Consult your doctor for more details.

    A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.


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    Q: How to confirm the Product Quality before placing orders
    A:You can get free samples for some products,you only need to pay the shipping
    cost or arrange a courier to us and take the samples. You can send us your
    product specifications and requests,we will manufacture the products according
    to your requests.
    Q: What’s your MOQ
    A:For the high value product, our MOQ starts from 1g and generally starts
    from 1kgs. For other low price product, our MOQ starts from 10kg and 100kg.
    Q: Is there a discount
    A: Yes, for larger quantity, we alway support with better price.
    Q:How do you treat quality complaint
    First of all, our quality control will reduce the quality problem to near zero.
    If there is a quality problem caused by us, we will send you free goods for
    replacement or refund your loss.
    Q:How to contact us
    A:You can choose your interested products and send inquiry to us.You can
    dial our telephone directly, you will get our reply.
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    Professional packing with professional materials, and We'll give clients several Packing way to choose after you contact me through my email
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    Our company is a professional leading factory in China in pharmaceutical area, ach batch of steroid powders have to tested by our QC(quality control) department before they are allowed to sell.
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    We can pack your powders within 12 hours after your payment, and corresponding picture of your powders' parcel will be sent to you.
    We are one of the leading manufacturers and exporters in China. We specialize in anabolic steroids, peptides,SARMs,fat burner and pharmaceutical intermediates. If you have any questions of our products that you are interested in, please contact as without hesitate.

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    Price: Negotiated

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    Payment Terms: T/T, Western Union, MoneyGram, Bitcoin

    Supply Ability: 1000kg/Month

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